| Identification | Back Directory | [Name]
TETRAHYDROPIPERINE | [CAS]
23434-88-0 | [Synonyms]
Cosmoperine
Tetrahydropiperin
TETRAHYDROPIPERINE
1-Pentanone, 5-(1,3-benzodioxol-5-yl)-1-(piperidinyl)-
1-Pentanone, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)- | [EINECS(EC#)]
-0 | [Molecular Formula]
C17H23NO3 | [MDL Number]
MFCD17167032 | [MOL File]
23434-88-0.mol | [Molecular Weight]
289.37 |
| Chemical Properties | Back Directory | [Boiling point ]
261 °C(Press: 14 Torr) | [density ]
1.156±0.06 g/cm3(Predicted) | [solubility ]
DMF: 10 mg/mL; DMSO: 10 mg/mL; DMSO:PBS (pH 7.2) (1:7): 0.1 mg/mL; Ethanol: 10 mg/mL | [form ]
Solid | [pka]
-0.44±0.20(Predicted) | [color ]
White to off-white | [Cosmetics Ingredients Functions]
SKIN CONDITIONING | [LogP]
3.674 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow crystalline powder, easily soluble in chloroform and ethyl acetate, soluble in hot ethanol and hot benzene, insoluble in water and petroleum ether, derived from the dry near-ripe or ripe fruit of Piper nigrum L. | [Uses]
food and beverages
pharmaceutical | [Definition]
ChEBI: Tetrahydropiperine is a member of benzodioxoles. | [Biological Activity]
Tetrahydropiperine is a cyclohexyl analog of piperine, the first natural arylvaleramide from Piper longum. Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/aryl hydrocarbon hydroxylase (AHH; IC50=23 μM). | [target]
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