| Identification | Back Directory | [Name]
Cyclopropanecarboxylic acid, 2-[4-[7-cyclopropyl-5-[[(1R)-3,4-dihydro-1-methyl-2(1H)-isoquinolinyl]carbonyl]pyrazolo[1,5-a]pyrimidin-2-yl]-3-fluorophenyl]-, (1S,2S)- | [CAS]
2347368-51-6 | [Synonyms]
Cyclopropanecarboxylic acid, 2-[4-[7-cyclopropyl-5-[[(1R)-3,4-dihydro-1-methyl-2(1H)-isoquinolinyl]carbonyl]pyrazolo[1,5-a]pyrimidin-2-yl]-3-fluorophenyl]-, (1S,2S)- | [Molecular Formula]
C30H27FN4O3 | [MOL File]
2347368-51-6.mol | [Molecular Weight]
510.56 |
| Hazard Information | Back Directory | [Uses]
JNJ-7184 is a non-nucleoside inhibitor of the RSV-Large (L) polymerase, with the pEC50 and pCC50 of 7.86 and 4.29 in Hela cells, respectively. JNJ-7184 prevents RSV replication and transcription by inhibiting initiation or early elongation[1]. | [References]
[1] Brecht Bonneux, et al. JNJ-7184, a respiratory syncytial virus inhibitor targeting the connector domain of the viral polymerase. Antiviral Res. 2024 Jul:227:105907. DOI:10.1016/j.antiviral.2024.105907 |
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