ChemicalBook--->CAS DataBase List--->2348493-39-8

2348493-39-8

2348493-39-8 Structure

2348493-39-8 Structure
IdentificationBack Directory
[Name]

NUC-7738
[CAS]

2348493-39-8
[Synonyms]

NUC-7738
UNC-7738
NUC-7738;NUC 7738;NUC7738
[Molecular Formula]

C26H29N6O7P
[MOL File]

2348493-39-8.mol
[Molecular Weight]

568.52
Chemical PropertiesBack Directory
[Boiling point ]

785.0±70.0 °C(Predicted)
[density ]

1.52±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

13.52±0.60(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

NUC-7738, an aryloxy phosphoramidate of 3′-Deoxyadenosine, is a 5′-aryloxy phosphoramidate prodrug of 3′-Deoxyadenosine (3′-dA). NUC-7738 has potent cytotoxic activity against a panel of hematological cancer cell lines. NUC-7738 can be used in research of cancer[1].
[References]

[1] Serpi M, et, al. Synthesis and Characterization of NUC-7738, an Aryloxy Phosphoramidate of 3'-Deoxyadenosine, as a Potential Anticancer Agent. J Med Chem. 2022 Dec 8;65(23):15789-15804. DOI:10.1021/acs.jmedchem.2c01348
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