| Identification | Back Directory | [Name]
8-debenzoylpaeoniflorin | [CAS]
23532-11-8 | [Synonyms]
desbenzoylpaeoniflorin
8-debenzoylpaeoniflorin
8-O-Debenzoylpaeoniflorin
β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-tetrahydro-5-hydroxy-5b-(hydroxymethyl)-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl | [Molecular Formula]
C16H24O10 | [MDL Number]
MFCD31746808 | [MOL File]
23532-11-8.mol | [Molecular Weight]
376.36 |
| Hazard Information | Back Directory | [Uses]
8-Debenzoylpaeoniflorin, a monoterpene glycoside, is a natural product that could be isolated from the dried root of Paeonia lactiflora Pall. 8-Debenzoylpaeoniflorin has antihyperglycemic activity[1]. | [in vivo]
8-Debenzoylpaeoniflorin (1-10 mg/kg; i.v.; single dose) has antihyperglycemic activity and decreases plasma glucose levels in STZ-diabetic rats[1]. | Animal Model: | Male Wistar STZ-diabetic rats (210-250g)[1] | | Dosage: | 1, 5, and 10 mg/kg | | Administration: | Intravenous injection, single dose | | Result: | Decreased plasma glucose levels in a time- and dose-dependent manner in STZ-diabetic rats. |
| [References]
[1] Hsu FL, et, al. Antihyperglycemic effects of paeoniflorin and 8-debenzoylpaeoniflorin, glucosides from the root of Paeonia lactiflora. Planta Med. 1997 Aug;63(4):323-5. DOI:10.1055/s-2006-957692 |
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