| Identification | Back Directory | [Name]
t-Boc-Aminooxy-PEG7-bromide | [CAS]
2353410-15-6 | [Synonyms]
t-Boc-Aminooxy-PEG7-bromide | [Molecular Formula]
C21H42BrNO10 | [MDL Number]
MFCD31693706 | [MOL File]
2353410-15-6.mol | [Molecular Weight]
548.46 |
| Hazard Information | Back Directory | [Description]
t-Boc-Aminooxy-PEG7-bromide is a crosslinking reagent. The hydrophilic PEG7 spacer increases solubility in aqueous media. Bromide (Br) is a very good leaving group for nucleophilic reactions. The t-Boc-Aminooxy can be deprotected under mild acidic conditions. | [Uses]
t-Boc-Aminooxy-PEG7-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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