| Identification | Back Directory | [Name]
Pyrido[4,3-d]pyrimidin-7(6H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-2-methyl-6-(1-methylcyclopropyl)- | [CAS]
2359689-76-0 | [Synonyms]
SOS1-IN-3
Pyrido[4,3-d]pyrimidin-7(6H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-2-methyl-6-(1-methylcyclopropyl)- | [Molecular Formula]
C21H21F3N4O | [MOL File]
2359689-76-0.mol | [Molecular Weight]
402.41 |
| Hazard Information | Back Directory | [Uses]
SOS1-IN-3 is a potent SOS1 (son of sevenless homolog 1) inhibitor with an IC50 of 5 nM. SOS1-IN-3 has anticancer effects (WO2019122129A1; compound I-1)[1]. | [References]
[1] Juergen Ramharter, et al. Novel benzylamino substituted pyridopyrimidinones and derivatives as sos1 inhibitors. WO2019122129A1 |
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