| Identification | Back Directory | [Name]
1H-Isoindol-1-one, 2,3-dihydro-4-[4-methyl-6-[[[6-(trifluoromethyl)-3-pyridinyl]methyl]amino]-3-pyridinyl]- | [CAS]
2361556-35-4 | [Synonyms]
CSF1R-IN-12
1H-Isoindol-1-one, 2,3-dihydro-4-[4-methyl-6-[[[6-(trifluoromethyl)-3-pyridinyl]methyl]amino]-3-pyridinyl]- | [Molecular Formula]
C21H17F3N4O | [MOL File]
2361556-35-4.mol | [Molecular Weight]
398.38 |
| Chemical Properties | Back Directory | [Boiling point ]
629.4±55.0 °C(Predicted) | [density ]
1.360±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.66±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CSF1R-IN-12 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-12 has the potential for the research of cancer diseases (extracted from patent WO2019134661A1, compound 1)[1]. | [References]
[1] Wenyun Qian, et al. Isoindolinone and derivative thereof as csf-1r inhibitor. Patent WO2019134661A1. |
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