| Identification | Back Directory | [Name]
CMLD012072 | [CAS]
2368900-33-6 | [Synonyms]
CMLD012072
3H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 2-cyclopropyl-3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)- | [Molecular Formula]
C32H32N2O7 | [MDL Number]
MFCD34469622 | [MOL File]
2368900-33-6.mol | [Molecular Weight]
556.61 |
| Hazard Information | Back Directory | [Uses]
CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity[1]. | [References]
[1] Chu J, et al. Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors. Cell Chem Biol. 2019 Nov 21;26(11):1586-1593. DOI:10.1016/j.chembiol.2019.08.008 |
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MedChemExpress
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