| Identification | Back Directory | [Name]
1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- | [CAS]
2368903-18-6 | [Synonyms]
FHT-1015
1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- | [Molecular Formula]
C25H25N5O4S3 | [MOL File]
2368903-18-6.mol | [Molecular Weight]
555.69 |
| Chemical Properties | Back Directory | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Solid | [pka]
7.66±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
FHT-1015 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 67)[1]. | [Biological Activity]
FHT-1205 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 67)[1]. | [storage]
Store at -20°C | [References]
[1]. Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1. |
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