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2369053-68-7

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2369053-68-7 Structure

2369053-68-7 Structure
IdentificationBack Directory
[Name]

2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride
[CAS]

2369053-68-7
[Synonyms]

2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride
[Molecular Formula]

C14H18ClN5O
[MDL Number]

MFCD32201164
[MOL File]

2369053-68-7.mol
[Molecular Weight]

307.779
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

SMARCA-BD ligand 1 for PROTAC dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].
[References]

[1] Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680. DOI:10.1038/s41589-019-0294-6
Spectrum DetailBack Directory
[Spectrum Detail]

2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride(2369053-68-7)1HNMR
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