| Identification | Back Directory | [Name]
Sultopride hydrochloride | [CAS]
23694-17-9 | [Synonyms]
Batil
MS-5024
Stadorf
Bamotil
SULTOPRIDE HCL
Einecs 245-829-0
Barnetil Hydrochloride
Barnotil Hydrochloride
LIN 1418 Hydrochloride
sultropridechlorhydrate
SULTOPRIDE HYDROCHLORIDE
n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-benzamidhyd
n-(1-ethyl-2-pyrrolidylmethyl)-2-methoxy-5-ethylsulfonylbenzamidechlorhydra
n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-ethylsulfonylbenzamidehydroch
N-((1-Ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride
N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride
n-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulphonyl)-2-methoxybenzamide hydrochloride
N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide Monohydrochloride
N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulphonyl)-2-methoxybenzamide monohydrochloride | [EINECS(EC#)]
245-829-0 | [Molecular Formula]
C17H27ClN2O4S | [MDL Number]
MFCD01319147 | [MOL File]
23694-17-9.mol | [Molecular Weight]
390.93 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
181-182°C | [storage temp. ]
Refrigerator | [solubility ]
Acetonitrile (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Usage]
Dopamine D2-receptor antagonist. An antipsychotic | [Originator]
Barnetil,Delagrange,France,1976 | [Uses]
Dopamine D2-receptor antagonist. An antipsychotic | [Uses]
Dopamine D2-receptor antagonist. An antipsychotic. | [Manufacturing Process]
A solution of 17.22 g of N-ethyl-α-aminomethylpyrrolidine in 360 ml of
pyridine is placed in a 1 l balloon flask. A solution of 3.51 g of phosphorus
trichloride in 40 ml of pyridine is added at ambient temperature. After the
mixture has been stirred for 1 hour, 10 g of 2-methoxy-5-ethylsulfonylbenzoic
acid is introduced. The mixture is heated under reflux for 4 ? hours. After
cooling, the solvent is evaporated under vacuum and the residue is dissolved
in 200 ml of 20% sodium hydroxide. The solution is extracted with 200 ml of
chloroform.
The organic solution is dried and filtered and the solvent is evaporated under
vacuum; the residue is dissolved in 150 ml of ethanol and the solution is
acidified with hydrochloric acid. The hydrochloride is dried without heating and
recrystallized from 100 ml of absolute ethanol. 7.2 g of N-(1-ethyl-2-
pyrrolidyl-methyl-2-methoxy-5-ethylsulfonylbenzamide hydrochloride is
produced. Melting point: 190°C to 193°C. | [Therapeutic Function]
Neuroleptic |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
|