| Identification | Back Directory | [Name]
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE | [CAS]
23749-58-8 | [Synonyms]
luminor2
luminogren
luminophor2
Yellow 2GF
yellow-green490rt
Solvent Yellow 184
LABOTEST-BB LT00007121
luminoryellowgreen490rt
naphthoylenebenzimidazole
luminoforyellow-green490rt
1,8-Naphthoylene-1',2'-benzimidazole
7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOL
7H-7a,12-Diazaindeno[2,1-a]phenalene-7-one
7a,12-Diazaindeno[2,1-a]phenalene-7(7aH)-one
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
7h-benzimidazo(2,1-a)benz(de)isoquinolin-7-one
7H-Benzimidazol[2,1-a]benz[de]isochinolin-7-on
7H-Benzimidazo[2,1-a]benz[de]-7-isoquinolinone
7H-Benzimidazo[2,1-a]benzo[de]isoquinolin-7-one
Benzimidazo[2,1-a]benz[d,e]isoquinolion-7-one 98%
BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE
7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one98%
7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one 98%
7H-Benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one
1,8-naphthoilene-1,2-benzimidazole (Luminor yellow-green 490 RT) | [EINECS(EC#)]
245-865-7 | [Molecular Formula]
C18H10N2O | [MDL Number]
MFCD00056826 | [MOL File]
23749-58-8.mol | [Molecular Weight]
270.28 |
| Chemical Properties | Back Directory | [Melting point ]
189 °C | [Boiling point ]
613.6±38.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [form ]
powder | [pka]
2.05±0.20(Predicted) | [color ]
Bright yellow | [InChI]
InChI=1S/C18H10N2O/c21-18-13-8-4-6-11-5-3-7-12(16(11)13)17-19-14-9-1-2-10-15(14)20(17)18/h1-10H | [InChIKey]
NZBSAAMEZYOGBA-UHFFFAOYSA-N | [SMILES]
C12=NC3=CC=CC=C3N1C(=O)C1=CC=CC3=CC=CC2=C13 |
| Hazard Information | Back Directory | [Uses]
AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1]. | [Application]
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE is a derivative of benzimidazo[2,1-a]benz[d,e]isoquinolion-7-one fluorophore, which is known to enter the cells and localize into the acidic organelles[2]. | [Properties and Applications]
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TEST ITEMS
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SPECIFICATION
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APPEARANCE
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YELLOW POWDER
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SHADE
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GREENISH
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HEAT RESISTANCE
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260 °C min
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LIGHT FASTNESS
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5-6
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ACID RESISTANCE
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5
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ALKALI RESISTANCE
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5
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WATER RESISTANCE
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5
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DENSITY
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1.20 g/cm
3
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RESIDUE ON 80 MESH
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5.0% max
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WATER SOLUBLE
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1.0% max
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VOLATITE 105 °C
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1.0% max
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TINTING STRENGTH
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100-105 %
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WEIGHT METAL TOTAL
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50ppm max
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| [References]
[1] Elson DJ, et.al. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. DOI:10.1021/acsptsci.2c00253 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
AFINE CHEMICALS LIMITED
|
| Telephone: |
+86-571-85134551 +86-18958018566 |
| Website: |
www.afinechem.com/index.html |
|