| Identification | Back Directory | [Name]
Auristatin23 | [CAS]
2375388-36-4 | [Synonyms]
Auristatin23
Auristatin23, 10 mM in DMSO
((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-((4-((tert-Butoxycarbonyl)(methyl)amino)butyl)(methyl)amino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine
(2S)-2-[(2R)-2-[(R)-[(2S)-1-[(3R,4S,5S)-4-[(2S)-2-[(2S)-2-[(4-{[(tert-butoxy)carbonyl](methyl)amino}butyl)(methyl)amino]-3-methylbutanamido]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoyl]pyrrolidin-2-yl](methoxy)methyl]propanamido]-3-phenylpropanoic acid | [Molecular Formula]
C49H84N6O10 | [MOL File]
2375388-36-4.mol | [Molecular Weight]
917.24 |
| Hazard Information | Back Directory | [Uses]
Auristatin23, a conjugate of Auristatin F (HY-15583), is a cytotoxin. Auristatin23 exhibit cytotoxic activities towards targeted cells, including abnormal cells such as cancer cells, that are MDR+ [1]. | [References]
[1] Doronina SO, et. Hydrophobic auristatin f compounds and conjugates thereof. WO2019164987A1. |
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