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2376876-87-6

2376876-87-6 Structure

2376876-87-6 Structure
IdentificationBack Directory
[Name]

2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one
[CAS]

2376876-87-6
[Synonyms]

2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one
[Molecular Formula]

C25H21BrN4O2
[MOL File]

2376876-87-6.mol
[Molecular Weight]

489.36
Chemical PropertiesBack Directory
[Boiling point ]

754.2±70.0 °C(Predicted)
[density ]

1.525±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[solubility ]

Soluble to 10 mM in DMSO
[pka]

10.31±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

CDK-IN-11 is a heterocyclic compound that has an action of promoting cardiomyocyte maturation[1].
[Biological Activity]

T 112 is an estrogen-related receptor gamma (ERRγ) agonist. Promotes maturation of hiPSC-derived cardiomyocytes. T 112 accelerates metabolic and sarcomere maturation in cardiomyocytes, as well as maturation of contractile and electrophysiological properties and ultrastructure organization, when used alone or in combination with other small molecules.
[storage]

Store at -20°C
[References]

[1] Yoshida S, et al. Heterocyclic compound. Japan, JPWO2019189553A1. 2021-03-25.
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