| Identification | Back Directory | [Name]
L-Histidine, L-threonyl-L-tryptophyl-L-prolyl-L-lysyl-L-histidyl-L-phenylalanyl-L-α-aspartyl-L-lysyl-L-histidyl-L-threonyl-L-phenylalanyl-L-tyrosyl-L-seryl-L-isoleucyl-L-leucyl-L-lysyl-L-leucylglycyl-L-lysyl- | [CAS]
2378836-93-0 | [Synonyms]
L57
L-Histidine, L-threonyl-L-tryptophyl-L-prolyl-L-lysyl-L-histidyl-L-phenylalanyl-L-α-aspartyl-L-lysyl-L-histidyl-L-threonyl-L-phenylalanyl-L-tyrosyl-L-seryl-L-isoleucyl-L-leucyl-L-lysyl-L-leucylglycyl-L-lysyl- | [Molecular Formula]
C120H175N31O27 | [MOL File]
2378836-93-0.mol | [Molecular Weight]
2483.87 |
| Chemical Properties | Back Directory | [density ]
1.319±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [Sequence]
Thr-Trp-Pro-Lys-His-Phe-Asp-Lys-His-Thr-Phe-Tyr-Ser-Ile-Leu-Lys-Leu-Gly-Lys-His |
| Hazard Information | Back Directory | [Uses]
L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with Ki of 45 nM. L57 exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 can be utilized as the carrier for CNS drug delivery[1]. | [References]
[1] Sakamoto K, et al., A novel LRP1-binding peptide L57 that crosses the blood brain barrier. Biochem Biophys Rep. 2017 Aug 12;12:135-139. DOI:10.1016/j.bbrep.2017.07.003 |
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Fuan Bio
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15002819872 |
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fuanbio.com |
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