| Identification | Back Directory | [Name]
Thalidomide-4-O-C10-COOH | [CAS]
2379870-45-6 | [Synonyms]
Thalidomide-4-O-C10-COOH
11-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]undecanoic Acid | [Molecular Formula]
C24H30N2O7 | [MOL File]
2379870-45-6.mol | [Molecular Weight]
458.51 |
| Chemical Properties | Back Directory | [Boiling point ]
704.561±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.290±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
4.779±0.10(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Thalidomide-4-O-C10-COOH is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs. | [IC 50]
Cereblon | [References]
[1] Powell CE, et al. Selective degradation-inducing probes for studying cereblon (CRBN) biology. RSC Med Chem. 2021 Jul 6;12(8):1381-1390. DOI:10.1039/d0md00382d |
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