| Identification | Back Directory | [Name]
Acetamide, 2-(2-aminoethoxy)-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, hydrochloride (1:1) | [CAS]
2380273-67-4 | [Synonyms]
2-(2-aminoethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide hydrochloride
Acetamide, 2-(2-aminoethoxy)-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, hydrochloride (1:1) | [Molecular Formula]
C17H19ClN4O6 | [MOL File]
2380273-67-4.mol | [Molecular Weight]
410.81 |
| Hazard Information | Back Directory | [Uses]
Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1]. | [References]
[1] Lee B, et al. Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug. J Enzyme Inhib Med Chem. 2023 Dec;38(1):51-66. DOI:10.1080/14756366.2022.2135510 |
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