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2382942-32-5

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2382942-32-5 Structure

2382942-32-5 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2382942-32-5
[Synonyms]

2’OC16-G(iBu) phosphoramidite
DMTr-2'-O-C16-rG(iBu)-3'-CE-Phosphoramidite
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl?guanosine?3’-CED?phosphoramidite
[Molecular Formula]

C60H86N7O9P
[MOL File]

2382942-32-5.mol
[Molecular Weight]

1080.36
Chemical PropertiesBack Directory
[pka]

8.68±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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