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2389988-22-9

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2389988-22-9 Structure

2389988-22-9 Structure
IdentificationBack Directory
[Name]

1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9- (beta-D-xylofuranosyl)guanine
[CAS]

2389988-22-9
[Synonyms]

1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9- (beta-D-xylofuranosyl)guanine
1H-Purine-6,8-dione, 1,2-diamino-7-(cyclopropylmethyl)-7,9-dihydro-9-β-D-xylofuranosyl-
[Molecular Formula]

C14H20N6O6
[MOL File]

2389988-22-9.mol
[Molecular Weight]

368.35
Chemical PropertiesBack Directory
[Boiling point ]

645.3±65.0 °C(Predicted)
[density ]

2.20±0.1 g/cm3(Predicted)
[pka]

13.40±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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