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2389988-23-0

2389988-23-0 Structure

2389988-23-0 Structure
IdentificationBack Directory
[Name]

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl) guanine
[CAS]

2389988-23-0
[Synonyms]

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(beta-D-ribofuranosyl)guanine
7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl) guanine
[Molecular Formula]

C14H19N5O6
[MDL Number]

MFCD34548950
[MOL File]

2389988-23-0.mol
[Molecular Weight]

353.33
Chemical PropertiesBack Directory
[Boiling point ]

614.8±65.0 °C(Predicted)
[density ]

2.14±0.1 g/cm3(Predicted)
[pka]

13.39±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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