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2389988-75-2

2389988-75-2 Structure

2389988-75-2 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2389988-75-2
[Synonyms]

2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine
[Molecular Formula]

C13H15N5O4
[MOL File]

2389988-75-2.mol
[Molecular Weight]

305.29
Chemical PropertiesBack Directory
[Boiling point ]

624.9±65.0 °C(Predicted)
[density ]

1.584±0.06 g/cm3(Predicted)
[pka]

13.85±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
2389988-75-2 suppliers list
Company Name: NewCan Biotech Limited  
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Telephone: 021-68689288 15300790979
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