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2389988-77-4

2389988-77-4 Structure

2389988-77-4 Structure
IdentificationBack Directory
[Name]

2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine
[CAS]

2389988-77-4
[Synonyms]

2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine
2',5'-Di-O-acetyl-8-benzyloxy-3'-deoxy-3'-fluoroguanosine
2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine
2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy-3'-fluoroguanosineconfidential
[Molecular Formula]

C21H22FN5O7
[MOL File]

2389988-77-4.mol
[Molecular Weight]

475.43
Chemical PropertiesBack Directory
[Boiling point ]

691.4±65.0 °C(Predicted)
[density ]

1.60±0.1 g/cm3(Predicted)
[pka]

2.09±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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