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23942-99-6

23942-99-6 Structure

23942-99-6 Structure
IdentificationBack Directory
[Name]

[S-(R*,S*)]-3,4-dimethoxy-alpha1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-o-xylene-alpha,alpha'-diol
[CAS]

23942-99-6
[Synonyms]

alpha-narcotinediol
(-)-α-Narcotinediol
1,2-Benzenedimethanol, 3,4-dimethoxy-α1-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (α1S)-
[S-(R*,S*)]-3,4-dimethoxy-alpha1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-o-xylene-alpha,alpha'-diol
[EINECS(EC#)]

245-946-7
[Molecular Formula]

C22H27NO7
[MOL File]

23942-99-6.mol
[Molecular Weight]

417.45
Chemical PropertiesBack Directory
[Melting point ]

130-132 °C(Solv: ethyl acetate (141-78-6); ethyl ether (60-29-7))
[Boiling point ]

570.3±50.0 °C(Predicted)
[density ]

1.300±0.06 g/cm3(Predicted)
[pka]

13.25±0.20(Predicted)
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

(-)-α-Narcotinediol is a Narcotine derivative, a noscapinoid class of microtubule binding compounds that alter microtubule dynamics without affecting tubulin polymer mass. Noscapinoids show great promise as chemotherapeutic agents for the treatment of human cancers. Unlike Narcotine, (-)-α-Narcotinediol deos not inhibit small-intestinal transport in rats.
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