| Identification | Back Directory | [Name]
1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- | [CAS]
2394874-60-1 | [Synonyms]
Axl/Mer/CSF1R-IN-1
1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- | [Molecular Formula]
C25H24F3N5O5 | [MOL File]
2394874-60-1.mol | [Molecular Weight]
531.48 |
| Hazard Information | Back Directory | [Uses]
Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R inhibitor with Kds of <0.1 μM[1]. | [IC 50]
Axl; Mer | [References]
[1] Kiyean NAM, et al. Quinoline derivatives as inhibitors of axl/mer rtk and csf1r. Patent WO2019229251A1. |
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