| Identification | Back Directory | [Name]
1H-Pyrrolo[2,3-b]pyridine, 5-[4-(4-methyl-1-piperazinyl)phenyl]-3-phenyl- | [CAS]
2403598-42-3 | [Synonyms]
HPK1-IN-18
1H-Pyrrolo[2,3-b]pyridine, 5-[4-(4-methyl-1-piperazinyl)phenyl]-3-phenyl- | [Molecular Formula]
C24H24N4 | [MOL File]
2403598-42-3.mol | [Molecular Weight]
368.47 |
| Hazard Information | Back Directory | [Uses]
HPK1-IN-18 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-18 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2019238067A1, compound 1)[1]. | [References]
[1] Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. Patent WO2019238067A1. |
|
|