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Alclofenac sodium is an anti-inflammatory agent used in the treatment of rheumatoid arthritis. | [Uses]
Alclofenac sodium is a non-steroidal anti-inflammatory agent (NSAID). Alclofenac sodium is a prostaglandin H2 synthase inhibitor. Alclofenac sodium can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research[1][2]. | [References]
[1] R N Brogden, et al. Alclofenac: a review of its pharmacological properties and therapeutic efficacy in rheumatoid arthritis and allied rheumatic disorders. Drugs. 1977 Oct;14(4):241-59. DOI:10.2165/00003495-197714040-00001
[2] B S Selinsky, et al. Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. Biochemistry. 2001 May 1;40(17):5172-80. DOI:10.1021/bi010045s |
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