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RBM10-8?is irreversible inhibitor of recombinant ?human sphingosine-1-phosphate lyase (hS1PL)?. Sphingosine-1-phosphate (S1P) is a sphingolipid (SL) that acts as a signaling molecule regulating diverse cellular processes such as cell proliferation and differentiation, angiogenesis, immune function, inflammation, and development[1]. | [References]
[1] Guillem Pons,?et al. A Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor. J Org Chem.?2020 Jan 17;85(2):419-429. DOI:10.1021/acs.joc.9b02420 |
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