| Identification | Back Directory | [Name]
hDDAH-1-IN-2 | [CAS]
2408834-77-3 | [Synonyms]
hDDAH-1-IN-2
hDDAH1IN2,hDDAH 1 IN 2
Guanidine, N''-(4-aminobutyl)-N-hydroxy-N'-(2-methoxyethyl)- | [Molecular Formula]
C8H20N4O2 | [MDL Number]
MFCD34549765 | [MOL File]
2408834-77-3.mol | [Molecular Weight]
204.27 |
| Hazard Information | Back Directory | [Uses]
hDDAH-1-IN-2 is a selective, orally active human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) inhibitor. hDDAH-1-IN-2 reveals an excellent profile regarding cell toxicity/viability[1]. | [References]
[1] Lunk I, et al. Discovery?of?N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine?as the?First?Selective,?Nonamino?Acid,?Catalytic?Site?Inhibitor?of?Human?Dimethylarginine?Dimethylaminohydrolase-1?(hDDAH-1).J Med Chem.?2020 Jan 9;63(1):425-432. DOI:10.1021/acs.jmedchem.9b01230 |
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