| Identification | Back Directory | [Name]
Dimethachlon | [CAS]
24096-53-5 | [Synonyms]
dsi
ohric
a6770
s-47127
ezomycin
Dimetachlone
DIMETHACHLON
Dimethachlone
dimethjachlon
N-(Dichlorophenyl)succinimide
N-（3，5-dichloropenyl) succinimide
n-(3,5-dichlorophenyl)-succinimid
N-(3,5-DICHLOROPHENYL)-SUCCINIMIDE
1-(3,5-dichlorophenyl)-5-pyrrolidinedione
5-Pyrrolidinedione,1-(3,5-dichlorophenyl)-2
1-(3,5-Dichlorophenyl)-2,5-pyrrolidinedione
1-(3,5-dichlorophenyl)pyrrolidine-2,5-dione
2,5-Pyrrolidinedione,1-(3,5-dichlorophenyl)-
1-(3,5-dichlorophenyl)pyrrolidine-2,5-quinone
DIMETHACHLON N-(3,5-DICHLOROPHENYL)- SUCCINIMIDE | [EINECS(EC#)]
601-478-9 | [Molecular Formula]
C10H7Cl2NO2 | [MDL Number]
MFCD00176441 | [MOL File]
24096-53-5.mol | [Molecular Weight]
244.07 |
| Chemical Properties | Back Directory | [Appearance]
white crystalline powder | [Melting point ]
136～140℃ | [Boiling point ]
493.9±35.0 °C(Predicted) | [density ]
1.4043 (rough estimate) | [refractive index ]
1.6100 (estimate) | [pka]
-2.68±0.20(Predicted) | [CAS DataBase Reference]
24096-53-5 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline powder | [Uses]
Dimethachlon is a fungicide found in pesticide compositions and is used in the treatment of necrotrophic fungal pathogen Sclerotinia sclerotiorum. | [Definition]
ChEBI:N-(3,5-Dichlorophenyl)succinimide is a member of pyrrolidines. | [Production Methods]
The production route for dimetachlone is not available in open literature. However, its production route can be inferred from its chemical identity and structure and would probably have followed the standard sequence for aryl substituted imides: chlorination or procurement of 3,5 dichloroaniline, conversion to the corresponding N aryl succinamic acid via condensation with succinic anhydride, and cyclodehydration to form the imide ring. The crude product would then be purified by crystallisation and drying to yield technical grade dimetachlone for formulation. | [Mechanism of action]
Limited systemic activity, mainly stomach but some contact action. Uncoupler of oxidative phosphorylation. | [Metabolic pathway]
The nephrotoxicant, N-(3,5-dichlorophenyl)succinimide
(NDPS), undergoes non-enzymatic hydrolysis to N-
(3,5-dichlorophenyl)succinamic acid (NDPSA) in
buffer, rat liver and kidney homogenates, and rabbit
liver homogenates. In the presence of NADPH, rat
liver homogenates convert NDPS to NDPSA and N-
(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-
NDHSA). Using liver homogenates from phenobarbital-
treated rats, N-(3,5-dichlorophenyl)-3-
hydroxysuccinimide (NDHS) and N-(3,5-
dichlorophenyl)-3-hydroxysuccinamic acid (3-NDHSA)
are also detected. | [Pesticide Type]
Fungicide |
|
|