| Hazard Information | Back Directory | [Uses]
PROTAC SMARCA2/4-degrader-28 (PROTAC 1) is a PROTAC-based partial degrader of SMARCA2 and SMARCA4(Bliue: CRL2VHL ligand (S,R,S)-AHPC (HY-125845); Black: linker (HY-159680); Pink: a SMARCA-BD ligand (+)-JQ-1 (HY-13030))[1]. | [References]
[1] Angus D Cowan, et al. Driving E3 Ligase Substrate Specificity for Targeted Protein Degradation: Lessons from Nature and the Laboratory. Annu Rev Biochem. 2022 Jun 21:91:295-319. DOI:10.1146/annurev-biochem-032620-104421 |
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