| Chemical Properties | Back Directory | [Boiling point ]
613.3±55.0 °C(Predicted) | [density ]
1.108±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
13.83±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
YOK-2204 is a ligand of p62-ZZ domain. YOK-2204 can activate p62-dependent selective macroautophagy. YOK-2204 can be used for AUTOTAC design[1]. | [References]
[1] Ji CH, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022 Feb 16;13(1):904. DOI:10.1038/s41467-022-28520-4 |
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