| Identification | Back Directory | [Name]
Taurodeoxycholic Acid-[d4] Sodium Salt | [CAS]
2410279-82-0 | [Synonyms]
Taurodeoxycholic Acid-[d4] Sodium Salt | [Molecular Formula]
C26H46NNaO6S | [MDL Number]
MFCD29472020 | [MOL File]
2410279-82-0.mol | [Molecular Weight]
523.7 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 3 mg/ml | [form ]
A crystalline solid | [CAS Number Unlabeled]
1180-95-6 |
| Hazard Information | Back Directory | [Description]
Taurodeoxycholic acid-d4 is intended for use as an internal standard for the quantification of taurodeoxycholic acid by GC- or LC-MS. Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid. Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally. Serum levels of taurodeoxycholic acid increase approximately 5-fold within two hours during an oral lipid tolerance test in humans. | [Uses]
Taurodeoxycholic acid-d4 (sodium) is the deuterium labeled Taurodeoxycholic acid[1]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110 |
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| Company Name: |
ChemeGen
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| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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