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2411088-16-7

2411088-16-7 Structure

2411088-16-7 Structure
IdentificationBack Directory
[Name]

Phenol, 4-[5-[[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethyl]amino]methyl]-2-furanyl]-
[CAS]

2411088-16-7
[Synonyms]

5-HT6/5-HT2A receptor ligand-2
Phenol, 4-[5-[[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethyl]amino]methyl]-2-furanyl]-
[Molecular Formula]

C20H18FN3O2
[MOL File]

2411088-16-7.mol
[Molecular Weight]

351.37
Chemical PropertiesBack Directory
[density ]

1.327±0.06 g/cm3(Predicted)
[pka]

9.44±0.15(Predicted)
Hazard InformationBack Directory
[Uses]

5-HT6/5-HT2A receptor ligand-2 (compound 42) is a brain-penetrant dual 5-HT6/5-HT2A receptor antagonist, with a Ki of 25 nM and?32?nM, respectively. 5-HT6/5-HT2A receptor ligand-2 shows pro-cognitive properties[1].
[IC 50]

5-HT6 Receptor: 25 nM (Ki); 5-HT2A Receptor: 32 nM (Ki)
[References]

[1] Staroń J, et, al. Virtual screening-driven discovery of dual 5-HT 6/5-HT 2A receptor ligands with pro-cognitive properties. Eur J Med Chem. 2020 Jan 1;185:111857. DOI:10.1016/j.ejmech.2019.111857
2411088-16-7 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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