| Identification | Back Directory | [Name]
[1,1'-Biphenyl]-3-sulfonamide, N,N-diethyl-3',4'-dimethoxy-6-[(3R)-1-methyl-5-oxo-3-pyrrolidinyl]- | [CAS]
2414195-69-8 | [Synonyms]
BET bromodomain inhibitor 2
1,1'-Biphenyl]-3-sulfonamide, N,N-diethyl-3',4'-dimethoxy-6-[(3R)-1-methyl-5-oxo-3-pyrrolidinyl]-
[1,1'-Biphenyl]-3-sulfonamide, N,N-diethyl-3',4'-dimethoxy-6-[(3R)-1-methyl-5-oxo-3-pyrrolidinyl]- | [Molecular Formula]
C23H30N2O5S | [MOL File]
2414195-69-8.mol | [Molecular Weight]
446.56 |
| Hazard Information | Back Directory | [Uses]
BET bromodomain inhibitor 2 is a potent BET bromodomain inhibitor with an IC50 of 14.1 μM[1]. | [References]
[1] J P Hilton-Proctor, et al. Substituted 1-methyl-4-phenylpyrrolidin-2-ones - Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors. Eur J Med Chem. 2020 Apr 1;191:112120. DOI:10.1016/j.ejmech.2020.112120 |
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