| Chemical Properties | Back Directory | [Boiling point ]
2201.4±65.0 °C(predicted) | [density ]
1.355±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
3.15±0.10(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
DT-6 is an effective TGF-β1 inhibitor. DT-6 inhibits M2 macrophage induced epithelial to mesenchymal transition and invasive migration of cancer cells. DT-6 can be used for cancer diseases research[1]. | [References]
[1] Feng Y, et al. Degradation of intracellular TGF-β1 by PROTACs efficiently reverses M2 macrophage induced malignant pathological events. Chem Commun (Camb). 2020 Mar 5;56(19):2881-2884. DOI:10.1039/c9cc08391j |
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