ChemicalBook--->CAS DataBase List--->2414373-42-3

2414373-42-3

Request For Quotation
2414373-42-3 Structure

2414373-42-3 Structure
IdentificationBack Directory
[Name]

4-[5-(4-Pyridylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide
[CAS]

2414373-42-3
[Synonyms]

DUN73423
RETV804M inhibitor
4-[5-(4-Pyridylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide
[Molecular Formula]

C19H16N6O
[MOL File]

2414373-42-3.mol
[Molecular Weight]

344.37
Chemical PropertiesBack Directory
[density ]

1.38±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

15.59±0.50(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

DUN73423 is a RET/KDR-Selective Inhibitor of RETV804M Kinase with IC50 = 7 nM. DUN73423 was listed in ACS Med Chem Lett . 2020 Feb 28;11(4):497-505 (compound 5). This product has no formal name at the moment.
[Uses]

RET-IN-21 is an inhibitor of receptor tyrosine kinase (RET), with the IC50 of 4.4 μM, that has antitumor activity[1].
[References]

[1] Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804M Kinase. ACS Med. Chem. Lett. 2020, 11, 4, 497–505
Spectrum DetailBack Directory
[Spectrum Detail]

4-[5-(4-Pyridylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide(2414373-42-3)1HNMR
2414373-42-3 suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Website: http://www.cw-bio.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: 021-QQ：65489617 15618227136
Website: www.atkchemical.com/
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Tel: 15865264761
Website: www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm
Company Name: InvivoChem  
Tel: 13549236410
Website: https://www.invivochem.cn/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Henan Alpha Chemical Co., Ltd.  
Tel: 0371-55013243 15324716602
Website: www.chemicalbook.com/supplier/24684125/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Z-trans Biochemistry Technology (Suzhou) Co.,Ltd  
Tel: 0512-66317708 13372112871
Website: http://zitrans.cn/
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Website: www.sangon.com
Company Name: Aikon International Limited  
Tel: 025-58859352 18651614124
Website: https://www.aikonchem.com/
Company Name: Biosynth Biological Technology (Suzhou) Co Ltd  
Tel: 51288865780
Website: www.biosynth.com
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Tel: 18916360931 18916360931
Website: www.amole.com.cn/
Company Name: Biorbyt Ltd.  
Tel: +44 (0)1223 859 353
Website: http://www.biorbyt.com
Company Name: Proteintech China  
Tel: 027-87531629
Website: http://www.ptgcn.com
Tags:2414373-42-3 Related Product Information