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2415374-97-7

2415374-97-7 Structure

2415374-97-7 Structure
IdentificationBack Directory
[Name]

(3S,4R)-GNE-6893
[CAS]

2415374-97-7
[Synonyms]

(3S,4R)-GNE-6893
[Molecular Formula]

C23H24FN5O4
[MOL File]

2415374-97-7.mol
[Molecular Weight]

453.47
Chemical PropertiesBack Directory
[Boiling point ]

642.613±55.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.437±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

10.973±0.43(predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

(3S,4R)-GNE-6893 is a potent and orally active HPK1 inhibitor. (3S,4R)-GNE-6893 can be used in research of cancer[1].
[References]

[1] Andreas S, et, al. A Convergent Synthesis of HPK1 Inhibitor GNE-6893 via Palladium-Catalyzed Functionalization of a Tetrasubstituted Isoquinoline. Org. Process Res. Dev. 2023;27(3):523-9.
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