ChemicalBook--->CAS DataBase List--->2416338-55-9

2416338-55-9

Request For Quotation
2416338-55-9 Structure

2416338-55-9 Structure
IdentificationBack Directory
[Name]

2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)-
[CAS]

2416338-55-9
[Synonyms]

Microtubule inhibitor 5
2,5-Piperazinedione, 3-[[3-(4-fluorophenoxy)phenyl]methylene]-6-(2-furanylmethylene)-, (3Z,6Z)-
[Molecular Formula]

C22H15FN2O4
[MOL File]

2416338-55-9.mol
[Molecular Weight]

390.36
Chemical PropertiesBack Directory
[Boiling point ]

695.8±55.0 °C(Predicted)
[density ]

1.371±0.06 g/cm3(Predicted)
[pka]

11.38±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Microtubule inhibitor 5 (compound 17f) is a potent microtubule inhibitor. Microtubule inhibitor 5 shows cytotoxicity with an IC50 value of 154.5 nM for NCI-H460 cells. Microtubule inhibitor 5 shows good cell permeability[1].
[References]

[1] Ding Z, et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435. DOI:10.1016/j.bmc.2020.115435
2416338-55-9 suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Telephone: 13816613772
Website: https://www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Telephone: hanfangpharma@126.com 18017580634
Website: hanfangpharma@126.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Tags:2416338-55-9 Related Product Information
54965-21-8 897016-82-9 474645-27-7 114977-28-5 253128-41-5 61-73-4