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2416569-95-2

2416569-95-2 Structure

2416569-95-2 Structure
IdentificationBack Directory
[Name]

3(2H)-Benzofuranone, 6-hydroxy-2-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, (2Z)-
[CAS]

2416569-95-2
[Synonyms]

Haspin-IN-3
3(2H)-Benzofuranone, 6-hydroxy-2-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, (2Z)-
[Molecular Formula]

C16H10N2O3
[MOL File]

2416569-95-2.mol
[Molecular Weight]

278.26
Chemical PropertiesBack Directory
[density ]

1.563±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

7.55±0.20(Predicted)
[color ]

Light yellow to brown
Hazard InformationBack Directory
[Uses]

Haspin-IN-3 (compound 8l) is a potent haspin inhibitor with IC50 of 14 nM. Haspin-IN-3 has anticancer effects[1].
[References]

[1] Malikotsi A Qhobosheane, et al. Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors. Bioorg Med Chem. 2020 Jun 1;28(11):115468. DOI:10.1016/j.bmc.2020.115468
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