Identification | Back Directory | [Name]
shikokianin | [CAS]
24267-69-4 | [Synonyms]
shikokianin 1α,11-Diacetoxy-7α,20-epoxy-6β,7-dihydroxykaur-16-en-15-one Kaur-16-en-15-one, 1,11-bis(acetyloxy)-7,20-epoxy-6,7-dihydroxy-, (1α,6β,7α)- | [Molecular Formula]
C24H32O8 | [MDL Number]
MFCD21364049 | [MOL File]
24267-69-4.mol | [Molecular Weight]
448.51 |
Chemical Properties | Back Directory | [Melting point ]
286-288 °C (decomp) | [Boiling point ]
581.4±50.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [pka]
10.75±0.70(Predicted) |
Hazard Information | Back Directory | [Uses]
Shikokianin, a diterpenoid, shows significant cytotoxicity against HL-60 and A-549 cells with IC50 values of 3.4 μM and 18.8 μM, respectively[1]. | [References]
[1] Su-Ping Bai, et al. Two novel ent-kauranoid diterpenoids from Isodon japonica leaves. Planta Med. 2005 Aug;71(8):764-9. DOI:10.1055/s-2005-871246 |
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