| Identification | Back Directory | [Name]
Benzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl- | [CAS]
2428737-43-1 | [Synonyms]
InhA-IN-2 InhA-IN-2, 10 mM in DMSO Benzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methy Benzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl- Benzo[b]thiophene2sulfonamide, N[3(aminomethyl)phenyl]5chloro3methyl,tuberculosis,Benzo[b]thiophene 2 sulfonamide, N [3 (aminomethyl)phenyl] 5 chloro 3 methyl ,Bacterial,inhibit,Mycobacterium tuberculosis,Inhibitor | [Molecular Formula]
C16H15ClN2O2S2 | [MOL File]
2428737-43-1.mol | [Molecular Weight]
366.89 |
| Hazard Information | Back Directory | [Uses]
InhA-IN-2 (Compound 23) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 0.31 μM[1]. | [References]
[1] Sabbah M, et al. Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. J Med Chem. 2020 May 14;63(9):4749-4761. DOI:10.1021/acs.jmedchem.0c00007 |
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