| Identification | Back Directory | [Name]
2-Quinazolinecarboxylic acid, 4-[3-fluoro-4-[[[(3-methylphenyl)amino]carbonyl]amino]phenoxy]-, ethyl ester | [CAS]
2439096-14-5 | [Synonyms]
VEGFR-2-IN-27
2-Quinazolinecarboxylic acid, 4-[3-fluoro-4-[[[(3-methylphenyl)amino]carbonyl]amino]phenoxy]-, ethyl ester | [Molecular Formula]
C25H21FN4O4 | [MOL File]
2439096-14-5.mol | [Molecular Weight]
460.46 |
| Hazard Information | Back Directory | [Uses]
VEGFR-2-IN-27 (compound 7a) is a highly potent VEGFR-2 inhibitor with an IC50 value of 14.8 nM. VEGFR-2-IN-27 can be used for researching anticancer[1]. | [IC 50]
VEGFR-2: 14.8 nM (IC50) | [References]
[1] Hadi SRAE, et al. Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors. Bioorg Chem. 2020 Aug;101:103961. DOI:10.1016/j.bioorg.2020.103961 |
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