| Identification | Back Directory | [Name]
Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- | [CAS]
2446136-17-8 | [Synonyms]
Aldose reductase-IN-4
Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- | [Molecular Formula]
C14H10FNO3S | [MOL File]
2446136-17-8.mol | [Molecular Weight]
291.3 |
| Hazard Information | Back Directory | [Uses]
Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1]. | [References]
[1] Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575. DOI:10.1016/j.bmc.2020.115575 |
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