| Identification | Back Directory | [Name]
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- | [CAS]
2446664-72-6 | [Synonyms]
FGFR3-IN-5
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- | [Molecular Formula]
C24H24FN7O3 | [MOL File]
2446664-72-6.mol | [Molecular Weight]
477.49 |
| Hazard Information | Back Directory | [Uses]
FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1]. | [IC 50]
FGFR3: 3 nM (IC50); FGFR2: 44 nM (IC50); FGFR1: 289 nM (IC50) | [References]
[1] James FB, et, al. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases. WO2020131627. |
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