| Identification | Back Directory | [Name]
1H-Pyrazole-5-carboxamide, N-[(1R)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)- | [CAS]
2446804-29-9 | [Synonyms]
1H-Pyrazole-5-carboxamide, N-[(1R)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)- | [Molecular Formula]
C27H34N6O2 | [MOL File]
2446804-29-9.mol | [Molecular Weight]
474.6 |
| Chemical Properties | Back Directory | [Boiling point ]
754.2±60.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (210.70 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
12.86±0.46(Predicted) | [color ]
Off-white to gray |
| Hazard Information | Back Directory | [Uses]
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4 (HY-141692). IL-17 modulator 4 is a proagent of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator[1]. | [Biological Activity]
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4 . IL-17 modulator 4 is a prodrug of IL-17 modulator 1 . IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator[1]. | [IC 50]
IL-17 | [storage]
Store at -20°C | [References]
[1]. Kevin Neil Dack, et al. Amino-acid anilides as small molecule modulators of il-17. WO2020127685A1. |
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