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2446816-88-0

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2446816-88-0 Structure

2446816-88-0 Structure
IdentificationBack Directory
[Name]

1H-Indole-3-propanamide, 5,7-difluoro-2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-
[CAS]

2446816-88-0
[Synonyms]

Inaxaplin
1H-Indole-3-propanamide, 5,7-difluoro-2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-
3-(5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl)-N-((3S,4R)-4-hydroxy-2-oxopyrrolidin-3-yl)propanamide
[Molecular Formula]

C21H18F3N3O3
[MOL File]

2446816-88-0.mol
[Molecular Weight]

417.38
Chemical PropertiesBack Directory
[Boiling point ]

797.6±60.0 °C(Predicted)
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml
[form ]

Solid
[pka]

13.03±0.40(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Inaxaplin (VX-147) is an orally active apolipoprotein L1 (APOL1) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease[1].
[storage]

Store at -20°C
[References]

[1] WO2020131807
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