| Identification | Back Directory | [Name]
Z-VAL-ALA-ASN-AMC | [CAS]
245036-58-2 | [Synonyms]
Z-VAN-AMC
Z-VAL-ALA-ASN-AMC
L-Aspartamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-alanyl-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- (9CI) | [Molecular Formula]
C30H35N5O8 | [MDL Number]
MFCD02259623 | [MOL File]
245036-58-2.mol | [Molecular Weight]
593.63 |
| Chemical Properties | Back Directory | [Boiling point ]
976.481±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.309±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
-15°C
| [pka]
11.050±0.46(predicted) | [Sequence]
Z-Val-Ala-Asn-{AMC} |
| Hazard Information | Back Directory | [Uses]
Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity[1][2]. | [References]
[1] Timo Burster, et al. Cathepsin G, and Not the Asparagine-Specific Endoprotease, Controls the Processing of Myelin Basic Protein in Lysosomes from Human B Lymphocytes1. J Immunol 1 May 2004; 172 (9): 5495–5503.
[2] Santamaría ME, et al. Digestive proteases in bodies and faeces of the two-spotted spider mite, Tetranychus urticae. J Insect Physiol. 2015 Jul;78:69-77. DOI:10.1016/j.jinsphys.2015.05.002 |
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