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Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM). | [References]
[1] Almeida-Souza F, et al. Nitric Oxide Induction in Peritoneal Macrophages by a 1,2,3-Triazole Derivative Improves Its Efficacy upon Leishmania amazonensisIn Vitro Infection. J Med Chem. 2021 Sep 9;64(17):12691-12704. DOI:10.1021/acs.jmedchem.1c00725 |
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