| Identification | Back Directory | [Name]
7Α,24(S)-DIHYDROXYCHOLESTEROL | [CAS]
245523-67-5 | [Synonyms]
7Α,24(S)-DIHYDROXYCHOLESTEROL
7α,24(S)-dihydroxy cholesterol
7alpha,24(S)-dihydroxycholesterol
Cholest-5-ene-3,7,24-triol, (3β,7α,24S)- | [Molecular Formula]
C27H46O3 | [MDL Number]
MFCD22416740 | [MOL File]
245523-67-5.mol | [Molecular Weight]
418.65 |
| Chemical Properties | Back Directory | [Boiling point ]
548.5±35.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
14.10±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
7α,24(S)-Dihydroxycholesterol is a sterol found to be,one of several, the most abundant cholesterol metabolite and an intermediate of bile acid biosynthetic pathways. | [General Description]
7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is synthetically synthesized via from E-α, β-enone from the starting compounds Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde. This undergoes further changes to form 7α,24(S)-dihydroxycholesterol. | [Biochem/physiol Actions]
7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is a ligand for liver X receptor (LXR) and binds to the ligand binding domain of LXRα and LXRβ. |
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