| Identification | Back Directory | [Name]
2H-1-Benzopyran-2-one, 3-amino-6-methoxy-7-[3-[[5-oxido-4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]oxy]propoxy]- | [CAS]
2460735-29-7 | [Synonyms]
Antitumor agent-62
2H-1-Benzopyran-2-one, 3-amino-6-methoxy-7-[3-[[5-oxido-4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]oxy]propoxy]- | [Molecular Formula]
C21H19N3O9S | [MOL File]
2460735-29-7.mol | [Molecular Weight]
489.46 |
| Hazard Information | Back Directory | [Uses]
Antitumor agent-62 (Compound 47) is a NO-releasing antitumor agent. Antitumor agent-62 shows antiproliferative activity against four cancer cell lines. Antitumor agent-62 activates mitochondrial apoptosis pathway and arrests cell cycle at G2/M phase[1]. | [References]
[1] Shi Z, et al. Novel NO-releasing scopoletin derivatives induce cell death via mitochondrial apoptosis pathway and cell cycle arrest. Eur J Med Chem. 2020 Aug 15;200:112386. DOI:10.1016/j.ejmech.2020.112386 |
|
|